Amitriptyline v Gabapentin

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Amitriptyline v Gabapentin

Postby carolad » Fri Jun 26, 2015 10:37 pm

I was at the GP today to see if there is anything else I can do to help with pain at night and sleep.

I've been on 50mg Amitriptyline for about a month (previously 30mg for about 5 years). He has suggested putting the dose up to 75mg but said that is a high dose for me so I might get too many side effects.

If that doesn't work out, he will try me on Gabapentin. I'd be interested to hear people's views on Gabapentin- good or bad! Also, if you've tried both Amitriptyline and Gabapentin- how did they compare?
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Re: Amitriptyline v Gabapentin

Postby Michelle1990 » Fri Jun 26, 2015 11:10 pm

Hi there I have been taking my amitriptyline on a 50mg dose for over 8 months now, I used to take them at night around half 10 but found it unhelpful and wasn't gettin 2 sleep until around 3am. It was so hard with me getting up around 6:40am I was in a vicious circle and found I was even more drained during the day. My chronic pain pysiotherapy told me to start taking them in the evening around 6:30pm and it's worked I am fast asleep by 11:30pm every night now. Regarding ur pain I totally understand n found it difficult myself and I am already on a high dose of gabapentin so all my doc could do is give me tramadol.
I really hope u start getting somewhere as I certainly know what it feels like when everything u try doesn't wrk. I have started 2 feel myself gaining more energy but atm we have to take it 1 step at a time just so you know what works best for you.
Good luck ☺ xx
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Re: Amitriptyline v Gabapentin

Postby Charley11 » Fri Jun 26, 2015 11:26 pm

Hi I've been on Amitriptyline 50mg for about 2 months now and have just started taking 3x300mg of gabapentin at night aswell as 2x 500mg of zapain and I have found that it helps me to have a more relaxed night. I am only on the Gabapentin for a months trial then I go back to the drs for a review, the only downside to it at the minute is that if I take the 3x300mg at night then it leaves me without for the next day,all I have to rely on then is my zapain until bedtime.Might be something you could talk with your dr about as everyone is different. I'm happy that I am giving it a go as it is the only thing that has worked up till now. Gentle hugs and hope you get sorted xx
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Re: Amitriptyline v Gabapentin

Postby Andyp » Fri Jun 26, 2015 11:31 pm

I have been on Gabapentin for a few years now, currently taking 4 x 300mg per day. I have found some days it seems to work better than others. However, I didn't take to Amitriptyline very well at all - it made me feel like somebody was forcing something into my eyes to force them to remain wide open, like Malcolm Mcdowelll's character in the film 'A Clockwork Orange', so I didn't stay on it for very long.
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Re: Amitriptyline v Gabapentin

Postby leeanne » Sat Jun 27, 2015 12:33 am

Hi huni I'm still trying to get my head round meds I'm on 100 mg of amitriptaline, I usually take at nine pm and still don't sleep till three am N I seem to sleep N wake in three hour intervals. Hope you find what works for you huni xx
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Re: Amitriptyline v Gabapentin

Postby leswaltdave » Sat Jun 27, 2015 7:21 am

Hi everyone
I have not tried Gabapentin but I am on 50mg per day of Amitriptyline.
I take 25mg first thing in the morning and 25mg at about 6pm and then 2 x 400mg Ibuprofen and 2 x tramadol at bed time (9pm),
This combination has helped with the pain at night and sleep has improved so much you wouldn't believe it.

My condition is worsened by stress at work so I am learning not to get worked up about anything. (It's hard)
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Re: Amitriptyline v Gabapentin

Postby migrembe » Sat Jun 27, 2015 7:39 am

Learn to meditate. Find some place that you can go to learn to meditate correctly or even try youtube or you can find out how on my blog. Also learn about mindfulness and learn to listen to your body and stop pushing your body to keep going when it wants to stop.

I had to stop Ami and gaby because of the bizarre side effects. I now take duloxtine, which has helped me a lot and i also take cocodamol, but that's it and i meditate every single day. I also meditate when the pain gets really bad in the middle of the night and it helps.

Meditation and mindfulness has helped me to listen to my body and stop, before the fatigue and pain takes over completely and i now sleep most nights at least 6 hours. I am still in pain and my body is still fatigued at times and there are some nights i sleep little, but i can now cope better with everything.

If you haven't tried it, then you should. Take some time with it over a few weeks. Don't worry about sitting in any fancy crossed-legged position, just sit or lie comfortably.

I hope it helps you as it has me.

Beverley x
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Re: Amitriptyline v Gabapentin

Postby fatalrazkaz » Sat Jun 27, 2015 8:53 pm

Tried Amitriptyline at 50mg but it left me too groggy in the mornings so tried Gabapentin. It was great for 3 years then I started to have really bad trouble with my brain. I couldn't concentrate, kept forgetting things, couldn't deal with anything so I decided to come off it. First couple of weeks was great, felt quite good, but then the sleepless nights started. I would see the sun rise and hear the birds start to sing and i hadn't even had any sleep. Then after about 5 weeks the pain hit me like a steam train. I didn't want to go back on the Gabapentin. Then we noticed something in Tesco that had been reduced and it said it was for backache and pain in the muscles and joints. We bought it and I have to say I'm quite surprised. That constant buzzing of pain that I had went, and I was back to how I was on the Gabapentin painwise. Its herbal and its called Devils Claw root extract. Try it, it seems to be working for me, what have you got to lose :-D xx
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Re: Amitriptyline v Gabapentin

Postby Icarus » Sat Jun 27, 2015 9:12 pm

I'll have to try that!!!


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Re: Amitriptyline v Gabapentin

Postby Icarus » Sat Jun 27, 2015 9:14 pm

Fatalrazkaz
What form does it come in? A cream or a tablet?


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Re: Amitriptyline v Gabapentin

Postby TheHud » Sat Jun 27, 2015 10:43 pm

Icarus wrote:Fatalrazkaz
What form does it come in? A cream or a tablet?


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Some info

http://www.nlm.nih.gov/medlineplus/drug ... l/984.html
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Re: Amitriptyline v Gabapentin

Postby Zia2014 » Sun Jun 28, 2015 12:40 pm

Amit helped me sleep but the effects wore off and I had to keep upping the dose for same results, which like you I didn't want to do. It was good on pain. Had v v bad constipation and that zombified feeling the next day til noon despite taking them early evening. Think I took 75mg.

Gaby was okay on pain, few side effects, bit of weight gain but stomach was okay and no zombie feeling. Had no impact on sleep whatsoever.
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Re: Amitriptyline v Gabapentin

Postby TheHud » Sun Jun 28, 2015 1:15 pm

Just a note again about gabapentin. GPs are required to give Lyrica (pregablin) for pain. it is a more advanced drug that is absorbed at 90% unlike gabapentine that only absorbs 30 - 66% depending on the person. The dose for pregablin is much lower and the side effects fewer to achieve the same results. It is significantly more expensive but also has immediate effect 0-1 hour unlike gab that minimum 3 hours but can be upto 6 hours or never.

It is down the list of choices because it is more expensive rather than not good. The list for our type of pain is amyl, doxy, gaba and last pregablin.

Hubby is a pain management specialist.
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Re: Amitriptyline v Gabapentin

Postby Zia2014 » Sun Jun 28, 2015 2:24 pm

TheHud wrote: The list for our type of pain is amyl, doxy, gaba and last pregablin.


I was given Amit, Nort, Naproxen, Gabapentin, Duloxetine, Pregabalin, Tramadol, then finally back to Pregabalin :crazy: :mrgreen:
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Re: Amitriptyline v Gabapentin

Postby galio » Mon Jun 29, 2015 11:15 am

I have a history of problems with medications where after a few weeks to a few months they start to work against me instead of for me so ... i started on am and it got to the point of taking it at 3pm to get the slightest sleep then it stopped me sleeping altogether but did help the pain, on advice of rhumy team gp changed me to nortriptyline this worked for a few months but on discussion with gp about increased dose when it was no longer helping it was found I shouldn't be on any triptyline type medication after a reaction many years a go(heart racing skipping beats etc) to a higher dose, another medication suggested was related to other antidepressants that my body rejects faster than they go :crazy: in so he said my choice was gabb or pregab and he suggested going straight to the pregabalin as its better, must say i started on an unbelievable low dose and since upping the dose after the first month (as recommended by manufacturer) I am still on lower than the starting dose and pain free a lot of the time cant say it does much for the sleep but as i'm not so sore i do sleep more some nights.
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